Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50014892
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)
Affinity DataKi:  16nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50580856(CHEMBL5074481)
Affinity DataKi:  140nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50139763(CHEMBL306657 | [(E)-(9S,10S,14S,18S)-18-Carbamoylm...)
Affinity DataIC50:  2nMAssay Description:Inhibition of GST-fused Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50580855(CHEMBL1205233)
Affinity DataIC50:  4.30nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50:  22nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50072862(CHEMBL117807 | Phosphoric acid mono-[4-((S)-2-acet...)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST-fused human Grb2-SH2 domain expressed in Escherichia coli by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)
Affinity DataIC50:  350nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50580856(CHEMBL5074481)
Affinity DataIC50:  740nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50060523(CHEMBL118574 | Phosphoric acid mono-(4-{(S)-2-acet...)
Affinity DataIC50:  8.64E+3nMAssay Description:Inhibition of GST-fused human Grb2-SH2 domain expressed in Escherichia coli by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50580857(CHEMBL5088383)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed