Found 108 Enz. Inhib. hit(s) with all data for entry = 50015583 
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human CB1 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Binding affinity to human CB2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor transfected in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity to to CB2 receptor (unknown origin) expressed in CHO -k1 cells assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity to to CB1 (unknown origin) expressed in CHO -k1 cells assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Displacement of [3H]CP55940 from mouse brain membrane CB1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity to CB1 (unknown origin) receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Binding affinity to to CB2 receptor (unknown origin) expressed in AtT20 cells assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Displacement of [35S]GTPgammaS from CB1 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Non competitive inhibition of recombinant human CYP2A6 using coumarin as substrate preincubated with NADPH for 20 mins and measured after 30 min by L...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to CB1 (unknown origin) receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity to CB1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+3nMAssay Description:Displacement of [3H]-WIN55212-2 from human CB2 receptor transfected in CHO cell membrane incubated for 90 mins by Liquid scintillation counter analys...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Mixed inhibition of recombinant CYP2B6 (unknown origin) using coumarin as substrate in presence of NADPH-generating system by Lineweaver-burk plots a...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Mixed inhibition of CYP2C19 (unknown origin) by measuring inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of human recombinant CYP1A1 preincubated with NADPH for 20 mins and measured after 30 min by Lineweaver-burk plots analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.55E+3nMAssay Description:Inhibition of recombinant human CYP2B6 using coumarin as substrate preincubated with NADPH for 20 mins and measured after 30 min by Lineweaver-burk p...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Displacement of [35S]GTPgammaS from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Displacement of [3H]-CP55940 from CB2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by measuring inhibition constant in presence of NADPH-generating system incubated for 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Mixed inhibition of recombinant human CYP2B6 using coumarin as substrate preincubated with NADPH for 20 mins and measured after 30 min by Lineweaver-...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at TRPM8 (unknown origin) ion channelMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant CYP1A1 (unknown origin) preincubated with NADPH for 20 mins and measured after 30 minMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Antagonist activity at TRPM8 (unknown origin) ion channelMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of isothiocyanateMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of icilinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of isothiocyanateMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of isothiocyanateMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of icilinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Homo sapiens)
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Agonist activity at ionomycin-stimulated TRPV2 (unknown origin) channel desensitization in presence of lysophosphatidylcholineMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of icilinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Antagonist activity at TRPM8 (unknown origin) desensitization in presence of icilinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV1 (unknown origin) channel desensitization in presence of capsaicinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV4 (unknown origin) channel desensitization in presence of 4alphaPDDMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of isothiocyanateMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Homo sapiens)
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV2 (unknown origin) channel desensitization in presence of lysophosphatidylcholineMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV3 (unknown origin) channel desensitization in presence of carvacrolMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Homo sapiens)
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV2 (unknown origin) channel desensitization in presence of lysophosphatidylcholineMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV1 (unknown origin) channel desensitization in presence of capsaicinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV4 (unknown origin) channel desensitization in presence of 4alphaPDDMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV3 (unknown origin) channel desensitization in presence of carvacrolMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 3.07E+3nMAssay Description:Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of isothiocyanateMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV4 (unknown origin) channel desensitization in presence of 4alphaPDDMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Mixed inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV4 (unknown origin) channel desensitization in presence of 4alphaPDDMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 5(Homo sapiens)
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of TRPV5 channel (unknown origin) by Patch-clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Inh (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV4 (unknown origin) channel desensitization in presence of 4alphaPDDMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Homo sapiens)
Scientus Pharma
Curated by ChEMBL
Scientus Pharma
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV2 (unknown origin) channel desensitization in presence of lysophosphatidylcholineMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Mixed inhibition of recombinant CYP2B6 (unknown origin) using coumarin as substrate in presence of NADPH-generating systemMore data for this Ligand-Target Pair
