Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 1986
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM350000((S)-(4,6-bis(trifluoromethyl)-1H- benzo[d]imidazol...)
Affinity DataIC50:  312nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Manual Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349999((2R)-2-amino-N-(2-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50:  436nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Manual Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349995((R)-2-amino-N-((S)-1-(3,5- bis(trifluoromethyl)phe...)
Affinity DataIC50:  568nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Manual Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349996((2R)-2-amino-N-(1-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50:  1.66E+3nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349997(2-amino-N-((S)-1-(3,5- bis(trifluoromethyl)phenoxy...)
Affinity DataIC50:  1.89E+3nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349995((R)-2-amino-N-((S)-1-(3,5- bis(trifluoromethyl)phe...)
Affinity DataIC50:  2.58E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349996((2R)-2-amino-N-(1-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50:  2.77E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM350000((S)-(4,6-bis(trifluoromethyl)-1H- benzo[d]imidazol...)
Affinity DataIC50:  2.89E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  3.50E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Manual Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349997(2-amino-N-((S)-1-(3,5- bis(trifluoromethyl)phenoxy...)
Affinity DataIC50:  4.12E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349999((2R)-2-amino-N-(2-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50:  5.32E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  8.12E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  9.62E+3nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349999((2R)-2-amino-N-(2-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50:  1.03E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349997(2-amino-N-((S)-1-(3,5- bis(trifluoromethyl)phenoxy...)
Affinity DataIC50:  1.15E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349996((2R)-2-amino-N-(1-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50:  1.27E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  1.50E+4nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (0.25HZ Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM350001((R)-2-amino-N-((4,6- bis(trifluoromethyl)-1H- benz...)
Affinity DataIC50:  1.50E+4nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM350001((R)-2-amino-N-((4,6- bis(trifluoromethyl)-1H- benz...)
Affinity DataIC50:  1.50E+4nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM350001((R)-2-amino-N-((4,6- bis(trifluoromethyl)-1H- benz...)
Affinity DataIC50:  1.50E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  1.50E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349995((R)-2-amino-N-((S)-1-(3,5- bis(trifluoromethyl)phe...)
Affinity DataIC50:  1.55E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  2.32E+4nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (7HZ Manual Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent