Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 8692
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223491(US10407441, Compound JQ6 | US10925881, Name (S)-JQ...)
Affinity DataIC50:  0.240nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223492(US10407441, Compound JQ8 | US10925881, Name (S)-JQ...)
Affinity DataIC50:  0.427nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223493(US10407441, Compound JQ13 | US10925881, Name (S)-J...)
Affinity DataIC50:  0.584nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223492(US10407441, Compound JQ8 | US10925881, Name (S)-JQ...)
Affinity DataIC50:  2.19nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223493(US10407441, Compound JQ13 | US10925881, Name (S)-J...)
Affinity DataIC50:  2.49nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223491(US10407441, Compound JQ6 | US10925881, Name (S)-JQ...)
Affinity DataIC50:  3.48nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223495(US10407441, Compound JQ35 | US9320741, JQ35)
Affinity DataIC50:  6.13nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)
Affinity DataIC50:  14nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)
Affinity DataIC50:  18nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223495(US10407441, Compound JQ35 | US9320741, JQ35)
Affinity DataIC50:  24.3nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223494(US10407441, Compound JQ33 | US9320741, JQ33)
Affinity DataIC50:  29.5nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223494(US10407441, Compound JQ33 | US9320741, JQ33)
Affinity DataIC50:  85nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataIC50:  8.35E+6nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataIC50:  5.21E+7nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
In DepthDetails US Patent