Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50027784
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247128((6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazo...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247129(1,3-dicycloheptyl-2-((6,6-dimethyl-5,6-dihydroimid...)
Affinity DataIC50:  8.80nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247015(1,3-dicycloheptyl-2-((5,6-dihydroimidazo[2,1-b]thi...)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247016(1,3-dicyclooctyl-2-((5,6-dihydroimidazo[2,1-b]thia...)
Affinity DataIC50:  27nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247017(1-cycloheptyl-3-cyclohexyl-2-((5,6-dihydroimidazo[...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247056(1-cyclohexyl-3-cyclooctyl-2-((5,6-dihydroimidazo[2...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50246956(1,3-dicyclohexyl-2-((5,6-dihydroimidazo[2,1-b]thia...)
Affinity DataIC50:  48nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247060(1-Adamantan-2-yl-3-cyclohexyl-2-(5,6-dihydro-imida...)
Affinity DataIC50:  81nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50246955(CHEMBL506505 | N-{3-[(2S,5S,8S,14R)-5-(3-Guanidino...)
Affinity DataIC50:  109nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247127(1,3-dicyclohexyl-2-((6,7-dihydro-5H-thiazolo[3,2-a...)
Affinity DataIC50:  185nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataIC50:  245nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247057(1-cyclohexyl-3-cyclopentyl-2-((5,6-dihydroimidazo[...)
Affinity DataIC50:  372nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247058(1-cyclohexyl-2-((5,6-dihydroimidazo[2,1-b]thiazol-...)
Affinity DataIC50:  855nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247095(1-(4-tert-butylcyclohexyl)-3-cyclohexyl-2-((5,6-di...)
Affinity DataIC50:  1.53E+3nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247059(1-Adamantan-1-yl-3-cyclohexyl-2-(5,6-dihydro-imida...)
Affinity DataIC50:  1.87E+3nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50246957(1,3-dicyclohexyl-2-((5,6-dihydroimidazo[2,1-b]thia...)
Affinity DataIC50:  3.58E+3nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247013(1,3-dicyclopentyl-2-((5,6-dihydroimidazo[2,1-b]thi...)
Affinity DataIC50:  3.84E+3nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247126(2-Benzo[4,5]imidazo[2,1-b]thiazol-3-ylmethyl-1,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247099(1,3-dicyclohexyl-2-(((E)-3-methyl-2-(methylimino)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247098(2-Benzyl-1,3-dicyclohexyl-isothiourea | CHEMBL4604...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247097(1-benzyl-3-cyclohexyl-2-((2,3,5,6-tetrahydroimidaz...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247014(2-(5,6-Dihydro-imidazo[2,1-b]thiazol-3-ylmethyl)-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50247096(1-cyclohexyl-2-((5,6-dihydroimidazo[2,1-b]thiazol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]CXCL12 from CXCR4 in human CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed