Compile Data Set for Download or QSAR
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Found 20 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50013607
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)
Affinity DataIC50:  150nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50:  3.43E+3nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50235921(CHEMBL584991)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568051(CHEMBL4092918)
Affinity DataIC50:  4.35E+3nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568044(CHEMBL4296926)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50013793(CHEMBL3192687)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM58106(6-(1,3-dihydrophenanthr[9,10-d]imidazol-2-ylidene)...)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568045(CHEMBL4296952)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568046(CHEMBL2000037)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568050(CHEMBL4296947)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50425026(CHEMBL241898)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM66065(5-fluoranyl-7-nitro-quinolin-8-ol | 5-fluoro-7-nit...)
Affinity DataIC50:  3.02E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM91466(10-(2-methoxyethyl)-3-phenyl-benzo[g]pteridine-2,4...)
Affinity DataIC50:  3.37E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM61215((5-amino-1-naphthalenyl)arsonic acid | (5-amino-1-...)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568047(CHEMBL4296835)
Affinity DataIC50:  4.33E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  4.86E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568048(CHEMBL1981840)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50568049(CHEMBL1487639)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed