Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50002393
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458066(CHEMBL4203016)
Affinity DataIC50:  23nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458060(CHEMBL4215076)
Affinity DataIC50:  29nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458067(CHEMBL4215080)
Affinity DataIC50:  30nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458062(CHEMBL4209019)
Affinity DataIC50:  34nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458058(CHEMBL4206166)
Affinity DataIC50:  44nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458068(CHEMBL4206716)
Affinity DataIC50:  45nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458063(CHEMBL4206288)
Affinity DataIC50:  53nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458069(CHEMBL4217992)
Affinity DataIC50:  58nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458065(CHEMBL4212884)
Affinity DataIC50:  66nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50458059(CHEMBL4209801)
Affinity DataIC50:  85nMAssay Description:Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed