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Compile Data Set for Download or QSAR
maximum 50k data
Found
25
Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50020227
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211424
(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211436
(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211430
((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211426
(2-((R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211438
(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211429
((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211428
(CHEMBL245936 | N-ethyl-4-(4-(2-phenyl-1H-indol-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211444
(CHEMBL245535 | N-(2-(4-(5-chloro-4-(1H-indol-3-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211443
((3S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211434
(CHEMBL245533 | ethyl 4-(5-chloro-4-(1H-indol-3-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211440
(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 41nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211442
(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211432
(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 57nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211427
(4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 59nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211439
((3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211446
(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211423
(4-(4-(1H-indol-1-yl)pyrimidin-2-ylamino)-N-ethylpi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 71nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211441
(4-(4-(1H-indol-3-yl)pyrimidin-2-ylamino)-N-ethylpi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211431
(4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 92nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211447
(2-((S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 139nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211445
(4-(4-(1H-indol-3-yl)-5-methylpyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 320nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211437
(3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 360nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211435
(4-(5-chloro-4-(1H-indol-1-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 457nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211433
(CHEMBL391794 | N-ethyl-4-(4-(2-isopropyl-1H-indol-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 520nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211425
(3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.34E+3nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI