TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.113nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.136nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.204nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nMMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nMMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nMMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.540nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.543nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.570nMAssay Description:Binding affinity to mouse kappa opioid receptor expressed in CHO cells in presence of U50488 incubated for 1.5 hrs by competitive radioligand binding...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cells after 1.5 hrsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:Displacement of [3H]diprenorphine from mouse KOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Evaluated for the binding affinity at kappa receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.770nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Binding affinity to mouse kappa opioid receptor expressed in CHO cells in presence of U50488 incubated for 1.5 hrs by competitive radioligand binding...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding ass...More data for this Ligand-Target Pair