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Found 4
TargetNLR family CARD domain-containing protein 4(Mus musculus)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50598203(CHEMBL5175251)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NLRC4 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr followed by flag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNLR family CARD domain-containing protein 4(Mus musculus)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50598211(CHEMBL5173327)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NLRC4 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr followed by flag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNLR family CARD domain-containing protein 4(Mus musculus)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50598209(CHEMBL5205215)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NLRC4 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr followed by flag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNLR family CARD domain-containing protein 4(Homo sapiens)
Jecure Therapeutics

Curated by ChEMBL
LigandPNGBDBM50607509(CHEMBL5219789)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of NLRC4 inflammasome activation in LPS/flagellin-treated human THP-1 cells preincubated with LPS for 3 hrs followed by compound addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed