Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50009216
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50: 0.240nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081415((S)-7-(3,5-Bis-trifluoromethyl-benzyl)-9-methyl-5-...)
Affinity DataIC50: 0.280nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50: 0.340nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081413(CHEMBL130834 | (S)-7-(3,5-Bis-trifluoromethyl-benz...)
Affinity DataIC50: 0.380nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081414(7-(3,5-Bis-trifluoromethyl-benzyl)-5-p-tolyl-7,8,9...)
Affinity DataIC50: 0.850nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081412(7-(3,5-Bis-trifluoromethyl-benzyl)-5-p-tolyl-7,8,9...)
Affinity DataIC50: 1.80nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081417(6-(3,5-Bis-trifluoromethyl-benzyl)-10-p-tolyl-7,8-...)
Affinity DataIC50: 2.30nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50: 4.20nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50: 4.20nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081419((R)-7-(3,5-Bis-trifluoromethyl-benzyl)-9-methyl-5-...)
Affinity DataIC50: 9.5nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081420((7S,9R)-7-(3,5-Bis-trifluoromethyl-benzyl)-9-methy...)
Affinity DataIC50: 20nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50081411(CHEMBL128586 | (7R,9S)-7-(3,5-Bis-trifluoromethyl-...)
Affinity DataIC50: 340nMAssay Description:Tachykinin receptor 1 antagonistic activity as ability to inhibit [125I]BH-SP binding in human IM-9 cells (lymphoblast cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed