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Found 26 Enz. Inhib. hit(s) with all data for entry = 50011425
TargetInsulin-like growth factor-binding protein 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  1nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 2(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  2.10nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.10nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.20nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.60nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  6.20nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106443(1-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-isoquinolin...)
Affinity DataKi:  7.5nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106446(6,7-Dihydroxy-1-(naphthalene-2-carbonyl)-isoquinol...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 2(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  17nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  21nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  24nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106439(6,7-Dihydroxy-1-(naphthalene-1-carbonyl)-isoquinol...)
Affinity DataKi:  27nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106441(1-(3,4-Dihydroxy-benzyl)-isoquinoline-3,6,7-triol ...)
Affinity DataKi:  29nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  34nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106433(1-(2,4-Dichloro-benzoyl)-6,7-dihydroxy-isoquinolin...)
Affinity DataKi:  44nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106436((6,7-Dihydroxy-isoquinolin-1-yl)-(3,4-dihydroxy-ph...)
Affinity DataKi:  58nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106437(5-Bromo-1-(3,4-dihydroxy-benzoyl)-6-hydroxy-7-meth...)
Affinity DataKi:  70nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106438(1-(Benzo[1,3]dioxole-5-carbonyl)-6,7-dihydroxy-iso...)
Affinity DataKi:  70nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  85nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106440(8-Bromo-1-(3,4-dihydroxy-benzoyl)-7-hydroxy-6-meth...)
Affinity DataKi:  140nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106435(7-Hydroxy-1-(3-hydroxy-4-methoxy-benzoyl)-6-methox...)
Affinity DataKi:  320nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106442(1-(3,4-Dihydroxy-benzoyl)-6,7-dimethoxy-isoquinoli...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106434(1-(3,4-Dimethoxy-benzoyl)-6,7-dimethoxy-isoquinoli...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106444(1-(3-Hydroxy-4-methoxy-benzoyl)-6,7-dimethoxy-isoq...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106445((3,4-Dimethoxy-phenyl)-(3-hydroxy-6,7-dimethoxy-is...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed