Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 50037228
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50079288(3-Cyclopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-c...)
Affinity DataKi:  6.70nMAssay Description:Tested for 5-hydroxytryptamine 4 receptor antagonist activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122872(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi:  7.5nMAssay Description:Tested for agonist activity against 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122876(4-Amino-5-chloro-2-methoxy-N-(1-methylamino-cyclop...)
Affinity DataKi:  9nMAssay Description:Tested for 5-hydroxytryptamine 3 receptor anatagonist activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122871(7-Amino-6-chloro-10,13-dioxa-2,16-diaza-tricyclo[1...)
Affinity DataKi:  29.7nMAssay Description:Tested for potency against 5-hydroxytryptamine 4 receptor agonist in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122871(7-Amino-6-chloro-10,13-dioxa-2,16-diaza-tricyclo[1...)
Affinity DataKi:  53.2nMAssay Description:Tested for 5-hydroxytryptamine 3 receptor agonist activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi:  84nMAssay Description:Tested for affinity against 5-hydroxytryptamine 4 receptor in the myenteric plexus of the guinea pigileum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50079306(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataKi:  91.9nMAssay Description:Tested for 5-hydroxytryptamine 4 receptor antagonist activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122872(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi:  110nMAssay Description:Tested for selectivity for 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi:  152nMAssay Description:Compound was tested for 5-hydroxytryptamine 3 receptor binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)
Affinity DataKi:  152nMAssay Description:Compound was tested for 5-hydroxytryptamine 3 receptor binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122878(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi:  420nMAssay Description:Compound was tested for selectivity against 5-hydroxytryptamine 3 receptor binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122872(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Tested for selectivity for 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122872(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Tested for selectivity for 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122878(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataEC50:  14nMAssay Description:Compound was tested for 5-hydroxytryptamine 4 binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataEC50:  23.7nMAssay Description:Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(MOUSE)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122873(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataEC50:  72nMAssay Description:Tested for ability to stimulate production of cAMP mediated by 5-hydroxytryptamine 4 receptor in mouse Colliculi neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122873(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataEC50:  40.3nMAssay Description:Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(MOUSE)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50122877(3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxy...)
Affinity DataEC50:  360nMAssay Description:Tested for ability to stimulate production of cAMP mediated by 5-hydroxytryptamine 4 receptor in mouse Colliculi neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed