Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50013928
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of Tyrosine-protein kinase receptor FLT3 (fms-related tyrosine kinase 3) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136019(9-ethoxymethyl-12-(3-hydroxypropyl)-6,7,12,13-tetr...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136018(9-(tert-butoxymethyl)-12-(3-hydroxypropyl)-6,7,12,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50024274(CHEMBL2448133)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory concentration against human vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136013(9-(sec-butoxymethyl)-12-(3-hydroxypropyl)-6,7,12,1...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136021(12-(3-hydroxypropyl)-9-propoxymethyl-6,7,12,13-tet...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136017(12-(3-hydroxypropyl)-9-methoxymethyl-6,7,12,13-tet...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136024(3-(9-isopropoxymethyl-5-oxo-6,7,12,13-tetrahydro-5...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136015(9-butoxymethyl-12-(3-hydroxypropyl)-6,7,12,13-tetr...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50024273(CHEMBL2112040)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory concentration against human vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136022(9-ethylsulfanylmethyl-12-(3-hydroxypropyl)-6,7,12,...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136020(9-(1-ethylpropoxymethyl)-12-(3-hydroxypropyl)-6,7,...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136030(12-(3-hydroxypropyl)-6,7,12,13-tetrahydro-5H-inden...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136031(9-isopropoxymethyl-6,7,12,13-tetrahydro-5H-indeno[...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of Proto-oncogene tyrosine-protein kinase KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136028(12-(3-hydroxypropyl)-9-isopropylsulfanylmethyl-6,7...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136016(12-(3-hydroxypropyl)-9-(1-methoxyethyl)-6,7,12,13-...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136025(9-bromo-12-(3-hydroxypropyl)-6,7,12,13-tetrahydro-...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136033(12-(3-hydroxypropyl)-5-oxo-6,7,12,13-tetrahydro-5H...)
Affinity DataIC50:  105nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136012(12-(2-hydroxyethyl)-6,7,12,13-tetrahydro-5H-indeno...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM14177(3,13-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136010(9-(1-hydroxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-...)
Affinity DataIC50:  111nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136029(9-(1-butoxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-t...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  162nMAssay Description:Inhibition of Fibroblast growth factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136023(9-methyl-12-(3-hydroxypropyl)-6,7,12,13-tetrahydro...)
Affinity DataIC50:  163nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136032(1-[12-(3-hydroxypropyl)-5-oxo-6,7,12,13-tetrahydro...)
Affinity DataIC50:  187nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136026(9-hydroxymethyl-12-(3-hydroxypropyl)-6,7,12,13-tet...)
Affinity DataIC50:  208nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136011(9-(1-ethoxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-t...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibitory concentration against human vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136011(9-(1-ethoxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-t...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136009(12-(3-hydroxypropyl)-9-isopentyloxymethyl-6,7,12,1...)
Affinity DataIC50:  276nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136014(12-(3-hydroxypropyl)-9-isopropylsulfinylmethyl-6,7...)
Affinity DataIC50:  309nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  406nMAssay Description:Inhibition of Platelet-derived growth factor receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136027(12-(3-hydroxypropyl)-9-(1-isopropoxyethyl)-6,7,12,...)
Affinity DataIC50:  411nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM14173(3,13-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,...)
Affinity DataIC50:  414nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  448nMAssay Description:Inhibition of c-Jun N-terminal kinase 1-beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of TrkA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of Serine/threonine-protein kinase Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of Serine/threonine-protein kinase Chk2 (CDS1 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha/beta/gamma type(Rattus norvegicus (Rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat brain Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tyrosine protein kinase receptor TIE-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of beta-insulin receptor kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed