Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 1670
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13166((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  12nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13180((2S)-1-[(2S)-3,3-dimethyl-2-[(2R)-2-(methylamino)p...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13168((2S)-N-[(1R)-2,3-dihydro-1H-inden-1-yl]-1-[(2S)-3,...)
Affinity DataKd:  29nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13169((2S)-N-[(1S)-2,3-dihydro-1H-inden-1-yl]-1-[(2S)-3,...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13170((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd: >500nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13171((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13172((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  47nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13173((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  167nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13174((2S,4S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamin...)
Affinity DataKd:  5nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13175((2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  16nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13176((2S,4S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamin...)
Affinity DataKd:  6nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13177((2S)-1-[(2S)-2-[(2S)-2-(dimethylamino)propanamido]...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13178((2S,4S)-1-[(2S)-2-[(2S)-2-(dimethylamino)propanami...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13179((2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(dimethylamino...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13167((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  706nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed