Compile Data Set for Download or QSAR
maximum 50k data
Found 57 Enz. Inhib. hit(s) with all data for entry = 50017992
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189670(5-{4-[(2S)-2-(5-chloro-1H-benzimidazol-2-yl)-2-({[...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189686(CHEMBL381584 | N-(1S)-1-(1H-benzimidazol-2-yl)-2-{...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189659(CHEMBL378614 | N-((1S)-1-(1H-benzimidazol-2-yl)-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189656(CHEMBL208114 | N-{(1S)-1-(1H-benzimidazol-2-yl)-2-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189687(CHEMBL211352 | N-((1S)-1-(1H-benzimidazol-2-yl)-2-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189642(CHEMBL210836 | N-(1S)-1-(1H-benzimidazol-2yl)-2-4-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189640(CHEMBL377989 | N-((1S)-1-(1H-benzimidazol-2-yl)-2-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM14268((2S)-N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)-2-{4-[(5S...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189635(CHEMBL424880 | N-((1S)-1-(1H-benzimidazol-2yl)-2-4...)
Affinity DataIC50:  43nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189649(CHEMBL212260 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  45nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189658(CHEMBL377735 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  48nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189657(CHEMBL208604 | N-(1S)-1-(1H-benzimidazol-2-yl)-2-{...)
Affinity DataIC50:  50nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189688(CHEMBL206950 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  51nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189655(CHEMBL207489 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  51nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189647(CHEMBL264833 | biphenyl-4-sulfonic acid {1-(5-cyan...)
Affinity DataIC50:  53nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189648(CHEMBL212147 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  60nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189673(CHEMBL383437 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  63nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189675(CHEMBL436933 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  67nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189679(CHEMBL210324 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  72nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189669(CHEMBL377441 | N-((1S)-1-(1H-benzimidazol-2yl)-2-{...)
Affinity DataIC50:  76nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189637(CHEMBL209107 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  77nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189654(CHEMBL210965 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  79nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189653(Biphenyl-4-sulfonic acid {1-(1H-benzoimidazol-2-yl...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189677(CHEMBL380164 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189681(CHEMBL208985 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189651(CHEMBL211076 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  85nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189660(CHEMBL211171 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  94nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189650(CHEMBL437119 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189645(CHEMBL377774 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189636(CHEMBL210159 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189676(CHEMBL207492 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189638(CHEMBL210837 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  120nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189665(CHEMBL378746 | biphenyl-4-sulfonic acid {1-(5-fluo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189680(CHEMBL209304 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189672(CHEMBL376950 | biphenyl-4-sulfonic acid {1-(5-meth...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189646(CHEMBL377978 | biphenyl-4-sulfonic acid {1-(5-meth...)
Affinity DataIC50:  140nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189643(CHEMBL378747 | biphenyl-4-sulfonic acid {1-(5-chlo...)
Affinity DataIC50:  140nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189671(CHEMBL264347 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  140nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189684(2-{1-(biphenyl-4-sulfonylamino)-2-[4-(1,1,3-trioxo...)
Affinity DataIC50:  150nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189662(CHEMBL377816 | biphenyl-4-sulfonic acid {1-(5-trif...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189644(CHEMBL209197 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189667(CHEMBL207645 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189683(CHEMBL211990 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189678(CHEMBL209180 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  170nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189689(CHEMBL208982 | biphenyl-4-sulfonic acid {1-(4-meth...)
Affinity DataIC50:  190nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM13465((2S)-N-[(1S)-1-carbamoyl-2-{4-[(5S)-1,1,3-trioxo-1...)
Affinity DataIC50:  240nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189682(CHEMBL377138 | biphenyl-4-sulfonic acid {1-(4-hydr...)
Affinity DataIC50:  240nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189668(CHEMBL208984 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  240nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189663(CHEMBL378992 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  280nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189685(CHEMBL377476 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  300nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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