Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50037820
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195157((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-3-me...)
Affinity DataIC50:  0.100nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195143((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-3,5-...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195151((8S,11R,13S,14S,17S)-11-(4-allyloxy-3-chloro-pheny...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195145((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-(4-me...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195160((8S,11R,13S,14S,17S)-17-hydroxy-11-(4'-methoxy-bip...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195158((8S,11S,13S,14S,17S)-11-(2,6-difluoro-4-methoxy-ph...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195153((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phen...)
Affinity DataIC50:  0.900nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195157((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-3-me...)
Affinity DataIC50:  1.10nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195155(A-348441 | CHEMBL219684)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195148((8S,11R,13S,14S,17S)-11-(4-allyloxy-3-chloro-5-met...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195154((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-(4-ph...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195145((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-(4-me...)
Affinity DataIC50:  1.80nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195149((4R)-4-[(1S,2S,5S,7R,9R,10R,11S,14R,15R,16S)-9,16-...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195143((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-3,5-...)
Affinity DataIC50:  2.80nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195146((4R)-4-[(1S,2S,5S,7R,9R,10R,11S,14R,15R,16S)-9,16-...)
Affinity DataIC50:  3.10nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195144((8S,11S,13S,14S,17S)-11-(2,5-difluoro-4-methoxy-ph...)
Affinity DataIC50:  3.20nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195160((8S,11R,13S,14S,17S)-17-hydroxy-11-(4'-methoxy-bip...)
Affinity DataIC50:  4.20nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195147((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-hydroxy-3-me...)
Affinity DataIC50:  4.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195151((8S,11R,13S,14S,17S)-11-(4-allyloxy-3-chloro-pheny...)
Affinity DataIC50:  4.70nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195150((4R)-4-[(1S,2S,5S,7R,9R,10R,11S,14R,15R,16S)-9,16-...)
Affinity DataIC50:  4.90nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  5nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195152((8S,11S,13S,14S,17S)-11-(2-fluoro-4,6-dimethoxy-ph...)
Affinity DataIC50:  6.10nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195153((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phen...)
Affinity DataIC50:  7.60nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195159((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-2-me...)
Affinity DataIC50:  9nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195155(A-348441 | CHEMBL219684)
Affinity DataIC50:  10nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195158((8S,11S,13S,14S,17S)-11-(2,6-difluoro-4-methoxy-ph...)
Affinity DataIC50:  10.1nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195144((8S,11S,13S,14S,17S)-11-(2,5-difluoro-4-methoxy-ph...)
Affinity DataIC50:  15nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195154((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-(4-ph...)
Affinity DataIC50:  18.8nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195148((8S,11R,13S,14S,17S)-11-(4-allyloxy-3-chloro-5-met...)
Affinity DataIC50:  20.9nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195149((4R)-4-[(1S,2S,5S,7R,9R,10R,11S,14R,15R,16S)-9,16-...)
Affinity DataIC50:  23.5nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195147((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-hydroxy-3-me...)
Affinity DataIC50:  28.6nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195146((4R)-4-[(1S,2S,5S,7R,9R,10R,11S,14R,15R,16S)-9,16-...)
Affinity DataIC50:  30.7nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195159((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-2-me...)
Affinity DataIC50:  32nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195152((8S,11S,13S,14S,17S)-11-(2-fluoro-4,6-dimethoxy-ph...)
Affinity DataIC50:  43nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195161((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-17-prop-...)
Affinity DataIC50:  60.7nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195150((4R)-4-[(1S,2S,5S,7R,9R,10R,11S,14R,15R,16S)-9,16-...)
Affinity DataIC50:  200nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195156((8S,11S,13S,14S,17S)-17-hydroxy-13-methyl-17-prop-...)
Affinity DataIC50:  482nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed