Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50037928
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  9nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  35nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199731(CHEMBL244883 | methotrexate gamma-hydroxamic acid)
Affinity DataIC50:  70nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199735(CHEMBL388879 | methotrexate gamma-L-proline-hydrox...)
Affinity DataIC50:  120nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199735(CHEMBL388879 | methotrexate gamma-L-proline-hydrox...)
Affinity DataIC50:  130nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Affinity DataIC50:  170nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199731(CHEMBL244883 | methotrexate gamma-hydroxamic acid)
Affinity DataIC50:  170nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Affinity DataIC50:  250nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50199731(CHEMBL244883 | methotrexate gamma-hydroxamic acid)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed