Compile Data Set for Download or QSAR
maximum 50k data
Found 56 Enz. Inhib. hit(s) with all data for entry = 50020304
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212293((1S,9R,10R)-5-amino-20-(cyclopropylmethyl)-6-thia-...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212293((1S,9R,10R)-5-amino-20-(cyclopropylmethyl)-6-thia-...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212297((1S,9R,10R)-5-amino-20-(cyclobutylmethyl)-6-thia-4...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212291((1S,13R,14R)-24-(cyclobutylmethyl)-4,24-diazahexac...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212293((1S,9R,10R)-5-amino-20-(cyclopropylmethyl)-6-thia-...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212297((1S,9R,10R)-5-amino-20-(cyclobutylmethyl)-6-thia-4...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212299((1S,9R,10R)-5-amino-20-methyl-6-thia-4,20-diazapen...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212291((1S,13R,14R)-24-(cyclobutylmethyl)-4,24-diazahexac...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212297((1S,9R,10R)-5-amino-20-(cyclobutylmethyl)-6-thia-4...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212292((1S,13R,14R)-24-(cyclopropylmethyl)-19-methoxy-4,2...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212292((1S,13R,14R)-24-(cyclopropylmethyl)-19-methoxy-4,2...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212299((1S,9R,10R)-5-amino-20-methyl-6-thia-4,20-diazapen...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212291((1S,13R,14R)-24-(cyclobutylmethyl)-4,24-diazahexac...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212299((1S,9R,10R)-5-amino-20-methyl-6-thia-4,20-diazapen...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212292((1S,13R,14R)-24-(cyclopropylmethyl)-19-methoxy-4,2...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212298((1S,13R,14R)-24-(cyclobutylmethyl)-19-methoxy-4,24...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212294((1S,13R,14R)-19-methoxy-24-methyl-4,24-diazahexacy...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212298((1S,13R,14R)-24-(cyclobutylmethyl)-19-methoxy-4,24...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212298((1S,13R,14R)-24-(cyclobutylmethyl)-19-methoxy-4,24...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212294((1S,13R,14R)-19-methoxy-24-methyl-4,24-diazahexacy...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212294((1S,13R,14R)-19-methoxy-24-methyl-4,24-diazahexacy...)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212291((1S,13R,14R)-24-(cyclobutylmethyl)-4,24-diazahexac...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO membrane assessed as inhibition of SNC80-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO membrane assessed as inhibition of SNC80-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO membrane assessed as inhibition of SNC80-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212293((1S,9R,10R)-5-amino-20-(cyclopropylmethyl)-6-thia-...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO membrane assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212297((1S,9R,10R)-5-amino-20-(cyclobutylmethyl)-6-thia-4...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212297((1S,9R,10R)-5-amino-20-(cyclobutylmethyl)-6-thia-4...)
Affinity DataIC50:  93nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO membrane assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212292((1S,13R,14R)-24-(cyclopropylmethyl)-19-methoxy-4,2...)
Affinity DataIC50:  440nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212291((1S,13R,14R)-24-(cyclobutylmethyl)-4,24-diazahexac...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212297((1S,9R,10R)-5-amino-20-(cyclobutylmethyl)-6-thia-4...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212292((1S,13R,14R)-24-(cyclopropylmethyl)-19-methoxy-4,2...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212299((1S,9R,10R)-5-amino-20-methyl-6-thia-4,20-diazapen...)
Affinity DataEC50:  21nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO membrane assessed as inhibition of U50488-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212299((1S,9R,10R)-5-amino-20-methyl-6-thia-4,20-diazapen...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212293((1S,9R,10R)-5-amino-20-(cyclopropylmethyl)-6-thia-...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212293((1S,9R,10R)-5-amino-20-(cyclopropylmethyl)-6-thia-...)
Affinity DataEC50:  0.340nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO membrane assessed as inhibition of U50488-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212291((1S,13R,14R)-24-(cyclobutylmethyl)-4,24-diazahexac...)
Affinity DataEC50:  190nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO membrane assessed as inhibition of U50488-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212292((1S,13R,14R)-24-(cyclopropylmethyl)-19-methoxy-4,2...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212292((1S,13R,14R)-24-(cyclopropylmethyl)-19-methoxy-4,2...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212298((1S,13R,14R)-24-(cyclobutylmethyl)-19-methoxy-4,24...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataEC50:  92nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50212296((1S,13R,14R)-24-(cyclopropylmethyl)-4,24-diazahexa...)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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