Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50021149
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212174(CHEMBL400438 | N-((5R,14R)-5-amino-5-methyl-4,16-d...)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM16041(3-{5-[(1R)-1-amino-1-methyl-2-phenylethyl]-1,3,4-o...)
Affinity DataIC50:  9nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221542(CHEMBL392361 | N-((R)-13-amino-13-methyl-14-oxo-15...)
Affinity DataIC50:  400nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221538(CHEMBL394225 | N-((R)-5-amino-5,14-dimethyl-4-oxo-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221537(CHEMBL235853 | N-((R)-5-amino-5,14-dimethyl-4-oxo-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221545(CHEMBL392564 | N-((5R,14R)-5-amino-5-methyl-4-oxo-...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221543(CHEMBL394224 | N-((R)-13-amino-2-cyclopropylmethyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221536(CHEMBL235854 | N-((R)-5-amino-5-methyl-4-oxo-14-ph...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221539(CHEMBL235645 | N-((R)-13-amino-2-benzyl-13-methyl-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221540(CHEMBL399595 | N-((R)-5-amino-5-methyl-4-oxo-3-oxa...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221541(CHEMBL238409 | N-(3-(5-((R)-2-amino-1-(4-fluorophe...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221544(CHEMBL442238 | N-((R)-13-amino-2-isopropyl-13-meth...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed