Compile Data Set for Download or QSAR
maximum 50k data
Found 57 Enz. Inhib. hit(s) with all data for entry = 50021767
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227724(CHEMBL400083 | N-hydroxy-2-methyl-2-{4-[2-methyl-3...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227723(2-{4-[3'-(2-amino-ethoxy)-2-methyl-biphenyl-4-yl]-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227725(2-{4-[3'-(2-dimethylamino-ethoxy)-2-methyl-bipheny...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227711(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227728(2-[4-(2-fluoro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227717(CHEMBL251916 | N-hydroxy-2-{4-[3'-(2-methoxy-ethox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227733(CHEMBL255030 | N-hydroxy-2-[4-(3'-methoxymethyl-2-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227710(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydr...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227721(2-[4-(2,3'-dimethyl-biphenyl-4-yl)-3,6-dihydro-2H-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227734(CHEMBL254817 | N-hydroxy-2-[4-(3'-methoxy-2-methyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227715(2-(4-biphenyl-4-yl-3,6-dihydro-2H-pyridine-1-sulfo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227715(2-(4-biphenyl-4-yl-3,6-dihydro-2H-pyridine-1-sulfo...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227719(CHEMBL254606 | N-hydroxy-2-[4-(2-methyl-biphenyl-4...)
Affinity DataIC50:  16nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227728(2-[4-(2-fluoro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50:  17nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-((S)-1-((S)-2-methoxy-1-phenylethylamino)-3,...)
Affinity DataIC50:  23nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227714(2-(4-biphenyl-4-yl-piperidine-1-sulfonyl)-N-hydrox...)
Affinity DataIC50:  26nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227727(2-[4-(3'-ethyl-2-methyl-biphenyl-4-yl)-3,6-dihydro...)
Affinity DataIC50:  31nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227730(CHEMBL398640 | N-hydroxy-2-[4-(2-methyl-3'-trifluo...)
Affinity DataIC50:  51nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227716(2-[4-(2-chloro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50:  55nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227732(2-[3-(biphenyl-4-yloxy)-azetidine-1-sulfonyl]-N-hy...)
Affinity DataIC50:  84nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227731(2-(3-biphenyl-4-yl-azetidine-1-sulfonyl)-N-hydroxy...)
Affinity DataIC50:  161nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227726(2-[(2-biphenyl-4-yl-ethyl)-methyl-sulfamoyl]-N-hyd...)
Affinity DataIC50:  164nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227730(CHEMBL398640 | N-hydroxy-2-[4-(2-methyl-3'-trifluo...)
Affinity DataIC50:  173nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227720(2-[(3-biphenyl-4-yl-propyl)-methyl-sulfamoyl]-N-hy...)
Affinity DataIC50:  174nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227723(2-{4-[3'-(2-amino-ethoxy)-2-methyl-biphenyl-4-yl]-...)
Affinity DataIC50:  188nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227724(CHEMBL400083 | N-hydroxy-2-methyl-2-{4-[2-methyl-3...)
Affinity DataIC50:  196nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227733(CHEMBL255030 | N-hydroxy-2-[4-(3'-methoxymethyl-2-...)
Affinity DataIC50:  196nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227729(CHEMBL400463 | N-hydroxy-2-(4-(4-phenoxyphenyl)pip...)
Affinity DataIC50:  205nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227734(CHEMBL254817 | N-hydroxy-2-[4-(3'-methoxy-2-methyl...)
Affinity DataIC50:  222nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  262nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227719(CHEMBL254606 | N-hydroxy-2-[4-(2-methyl-biphenyl-4...)
Affinity DataIC50:  320nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227735(2-(biphenyl-4-ylmethyl-methyl-sulfamoyl)-N-hydroxy...)
Affinity DataIC50:  378nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  406nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227713(2-[4-(2-ethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridi...)
Affinity DataIC50:  420nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227711(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine...)
Affinity DataIC50:  457nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  529nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227725(2-{4-[3'-(2-dimethylamino-ethoxy)-2-methyl-bipheny...)
Affinity DataIC50:  534nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227716(2-[4-(2-chloro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50:  620nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227721(2-[4-(2,3'-dimethyl-biphenyl-4-yl)-3,6-dihydro-2H-...)
Affinity DataIC50:  776nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227717(CHEMBL251916 | N-hydroxy-2-{4-[3'-(2-methoxy-ethox...)
Affinity DataIC50:  853nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227712(CHEMBL254816 | N-hydroxy-2-[4-(2-trifluoromethyl-b...)
Affinity DataIC50:  960nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227710(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydr...)
Affinity DataIC50:  998nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227727(2-[4-(3'-ethyl-2-methyl-biphenyl-4-yl)-3,6-dihydro...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  1.71E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-((S)-1-((S)-2-methoxy-1-phenylethylamino)-3,...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227712(CHEMBL254816 | N-hydroxy-2-[4-(2-trifluoromethyl-b...)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  3.23E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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