Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50003952
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477968(CHEMBL256616)
Affinity DataIC50:  23nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477982(CHEMBL403372)
Affinity DataIC50:  62nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157973(5-chloro-thiophene-2-sulfonic acid tricyclo[8.2.1....)
Affinity DataIC50:  63nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477979(CHEMBL402285)
Affinity DataIC50:  81nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477981(CHEMBL256384)
Affinity DataIC50:  105nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477973(CHEMBL255740)
Affinity DataIC50:  212nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477978(CHEMBL257231)
Affinity DataIC50:  257nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477972(CHEMBL258136)
Affinity DataIC50:  416nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477969(CHEMBL273144)
Affinity DataIC50:  491nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477970(CHEMBL269999)
Affinity DataIC50:  685nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477977(CHEMBL257230)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477975(CHEMBL272927)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477974(CHEMBL255767)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477971(CHEMBL404092)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477980(CHEMBL272926)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477976(CHEMBL437972)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed