Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50026350
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267151(10-N-Demethyl-10-N-(6-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  5.62nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267150(10-N-Demethyl-10-N-(5-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  6.52nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267157(10-N-Demethyl-10-N-(6-(4-((diethylamino)methyl)-ph...)
Affinity DataIC50:  8.86nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267106(10-N-Demethyl-10-N-(4-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  12.4nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267156(10-N-Demethyl-10-N-(4-(4-((diethylamino)methyl)-ph...)
Affinity DataIC50:  14.6nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267105(10-N-Demethyl-10-N-(3-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  18nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267104(10-N-Demethyl-10-N-(2-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  24.5nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267152(10-N-Demethyl-10-N-(8-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  34.7nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267190(10-N-Demethyl-10-N-(4-(4-(pyrrolidine-1-carbonyl)-...)
Affinity DataIC50:  53.8nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267155(10-N-Demethyl-10-N-(12-(4-(piperidin-1-ylmethyl)-p...)
Affinity DataIC50:  58.1nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267154(10-N-Demethyl-10-N-(10-(4-(piperidin-1-ylmethyl)-p...)
Affinity DataIC50:  61.2nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267153(10-N-Demethyl-10-N-(9-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  88.1nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267188(10-N-Demethyl-10-N-(4-(3-(1-morpholinoethyl)phenox...)
Affinity DataIC50:  94.1nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267186(10-N-Demethyl-10-N-(4-(4-(morpholinomethyl)phenoxy...)
Affinity DataIC50:  99.1nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267187(10-N-Demethyl-10-N-(6-(4-(morpholinomethyl)phenoxy...)
Affinity DataIC50:  113nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267191(10-N-Demethyl-10-N-(6-(4-(pyrrolidine-1-carbonyl)-...)
Affinity DataIC50:  122nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267189(10-N-Demethyl-10-N-(6-(3-(1-morpholinoethyl)phenox...)
Affinity DataIC50:  154nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267221(10-N-Demethyl-10-N-(6-(1-benzylpiperidin-4-yloxy)-...)
Affinity DataIC50:  222nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267220(10-N-Demethyl-10-N-(4-(1-benzylpiperidin-4-yloxy)-...)
Affinity DataIC50:  306nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267155(10-N-Demethyl-10-N-(12-(4-(piperidin-1-ylmethyl)-p...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267186(10-N-Demethyl-10-N-(4-(4-(morpholinomethyl)phenoxy...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267187(10-N-Demethyl-10-N-(6-(4-(morpholinomethyl)phenoxy...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267220(10-N-Demethyl-10-N-(4-(1-benzylpiperidin-4-yloxy)-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267221(10-N-Demethyl-10-N-(6-(1-benzylpiperidin-4-yloxy)-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267190(10-N-Demethyl-10-N-(4-(4-(pyrrolidine-1-carbonyl)-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267189(10-N-Demethyl-10-N-(6-(3-(1-morpholinoethyl)phenox...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267188(10-N-Demethyl-10-N-(4-(3-(1-morpholinoethyl)phenox...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267191(10-N-Demethyl-10-N-(6-(4-(pyrrolidine-1-carbonyl)-...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267104(10-N-Demethyl-10-N-(2-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267105(10-N-Demethyl-10-N-(3-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267106(10-N-Demethyl-10-N-(4-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267150(10-N-Demethyl-10-N-(5-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267151(10-N-Demethyl-10-N-(6-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267156(10-N-Demethyl-10-N-(4-(4-((diethylamino)methyl)-ph...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267157(10-N-Demethyl-10-N-(6-(4-((diethylamino)methyl)-ph...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267152(10-N-Demethyl-10-N-(8-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267153(10-N-Demethyl-10-N-(9-(4-(piperidin-1-ylmethyl)phe...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267154(10-N-Demethyl-10-N-(10-(4-(piperidin-1-ylmethyl)-p...)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed