Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 2686
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23400((2Z)-4-(3-benzylphenyl)-2-hydroxy-4-oxobut-2-enoic...)
Affinity DataIC50:  26nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23399(4-{1-[(4-fluorophenyl)methyl]-1H-pyrrol-2-yl}-2,4-...)
Affinity DataIC50:  37nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23401(6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2R)-1-hydr...)
Affinity DataIC50:  42nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23402(5-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(4-fluoropheny...)
Affinity DataIC50:  44nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23398((2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hy...)
Affinity DataIC50:  46nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23403(7-[(4-fluorophenyl)methyl]-9-hydroxy-5-methoxy-6H,...)
Affinity DataIC50:  60nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23405(7-[(4-fluorophenyl)methyl]-5-methoxy-6H,7H,8H-pyrr...)
Affinity DataIC50:  2.40E+4nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23404(7-[(4-fluorophenyl)methyl]-5,9-dimethoxy-6H,7H,8H-...)
Affinity DataIC50: >1.00E+6nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed