Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50038686
TargetMetabotropic glutamate receptor 1(RAT)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263670(1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in Syrian golden hamster BHK cells assessed as potentiation of glutamate-induced calcium flux by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263670(1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Activity at rat mGluR5 expressed in HEK cells assessed as potentiation of glutamate-induced calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263670(1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-...)
Affinity DataEC50:  4.60E+3nMAssay Description:Activity at human mGluR4 expressed in CHO coexpressing Gqi5 assessed as potentiation of glutamate-induced calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263669((1aS,7aS)-7-(hydroxyimino)-N-phenyl-1,1a,7,7a-tetr...)
Affinity DataEC50:  4.10E+3nMAssay Description:Activity at human mGluR4 expressed in CHO coexpressing Gqi5 assessed as potentiation of glutamate-induced calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed