Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 2868
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25537(4-(2-hydroxyethyl)-8-methyl-12,14-dioxa-8-azatetra...)
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25539(4-(2-methoxyethyl)-8-methyl-12,14-dioxa-8-azatetra...)
Affinity DataIC50:  6.00E+3nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25538(4-(methoxymethyl)-8-methyl-12,14-dioxa-8-azatetrac...)
Affinity DataIC50:  1.10E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25536(4-(hydroxymethyl)-8-methyl-12,14-dioxa-8-azatetrac...)
Affinity DataIC50:  1.10E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25530(8-methyl-12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}...)
Affinity DataIC50:  1.20E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25540(7,8-dihydroxy-5-methylphenanthridin-5-ium chloride...)
Affinity DataIC50:  1.80E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Affinity DataIC50:  1.90E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25541(7,8-dihydroxy-2-(hydroxymethyl)-5-methylphenanthri...)
Affinity DataIC50:  2.00E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25542(7,8-dihydroxy-2-(2-hydroxyethyl)-5-methylphenanthr...)
Affinity DataIC50:  2.20E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25533(8-oxido-12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25534(13,13-dimethyl-8-oxido-12,14-dioxa-8-azatetracyclo...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25535(2-(hydroxymethyl)-7,8-dimethoxy-5-methylphenanthri...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25529(7,8-dimethoxy-5-methylphenanthridin-5-ium iodide |...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25531(8,13,13-trimethyl-12,14-dioxa-8-azatetracyclo[8.7....)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25527(12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}.0^{11,15...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25526(7,8-dimethoxyphenanthridine | chelerythrine analog...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataIC50:  1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25532(7,8-dimethoxy-5-oxidophenanthridin-5-ium | chelery...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
A* Star

LigandPNGBDBM25528(13,13-dimethyl-12,14-dioxa-8-azatetracyclo[8.7.0.0...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed