Compile Data Set for Download or QSAR
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Found 29 Enz. Inhib. hit(s) with all data for entry = 50028131
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277017(4-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276987(7-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276988(2-(4-methylpiperazin-1-yl)-4-(naphthalen-1-ylsulfo...)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277019(2-(4-ethylpiperazin-1-yl)-4-(naphthalen-1-ylsulfon...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277021(2-(4-isopropylpiperazin-1-yl)-4-(naphthalen-1-ylsu...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277016(4-(2,5-dichlorophenylsulfonyl)-2-(piperazin-1-yl)b...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276985(2-(piperazin-1-yl)-4-(3-(trifluoromethyl)phenylsul...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276984(4-(4-isopropylphenylsulfonyl)-2-(piperazin-1-yl)be...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277015(4-(3-methoxyphenylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276983(4-(3-chlorophenylsulfonyl)-2-(piperazin-1-yl)benzo...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277014(2-(piperazin-1-yl)-4-(4-(trifluoromethyl)phenylsul...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277020(4-(naphthalen-1-ylsulfonyl)-2-(4-propylpiperazin-1...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277012(4-(phenylsulfonyl)-2-(piperazin-1-yl)benzo[d]oxazo...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277018(5-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277013(4-(3-fluorophenylsulfonyl)-2-(piperazin-1-yl)benzo...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276982(4-(4-fluorophenylsulfonyl)-2-(piperazin-1-yl)benzo...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276991(2-(4-cyclobutylpiperazin-1-yl)-4-(naphthalen-1-yls...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277023(2-(4-cyclopentylpiperazin-1-yl)-4-(naphthalen-1-yl...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277022(2-(4-butylpiperazin-1-yl)-4-(naphthalen-1-ylsulfon...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276990(4-(naphthalen-1-ylsulfonyl)-2-(4-phenethylpiperazi...)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276989(2-(4-isobutylpiperazin-1-yl)-4-(naphthalen-1-ylsul...)
Affinity DataKi:  176nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276986(6-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataKi:  196nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276987(7-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataIC50:  77nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277017(4-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataIC50:  96nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277015(4-(3-methoxyphenylsulfonyl)-2-(piperazin-1-yl)benz...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276988(2-(4-methylpiperazin-1-yl)-4-(naphthalen-1-ylsulfo...)
Affinity DataIC50:  105nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277016(4-(2,5-dichlorophenylsulfonyl)-2-(piperazin-1-yl)b...)
Affinity DataIC50:  117nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276985(2-(piperazin-1-yl)-4-(3-(trifluoromethyl)phenylsul...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277019(2-(4-ethylpiperazin-1-yl)-4-(naphthalen-1-ylsulfon...)
Affinity DataIC50:  248nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed