Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50028223
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248084((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-(5-methylfuran-...)
Affinity DataKi:  7.5nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247950((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-(5-methylfuran-...)
Affinity DataKi:  13nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248113((R)-N-(2-cyanoethyl)-3-(4-(2,2-dimethyl-1-(5-methy...)
Affinity DataKi:  13nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248115((R)-N-(2-cyanoethyl)-3-(4-(1-(furan-2-yl)-2,2-dime...)
Affinity DataKi:  14nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248038((R)-3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  14nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248082((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataKi:  14nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataKi:  15nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248039((R)-3-(4-(1-(furan-2-yl)-2,2-dimethylpropylamino)-...)
Affinity DataKi:  15nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248591((R)-3-(4-(cyclopropyl(phenyl)methylamino)-1,2,5-th...)
Affinity DataKi:  16nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248083((R)-(3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)prop...)
Affinity DataKi:  18nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248590((R)-3-(4-(1-(3,5-difluorophenyl)propylamino)-1,2,5...)
Affinity DataKi:  20nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248547((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-phenylpropylami...)
Affinity DataKi:  21nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248114((R)-N-(2-cyanoethyl)-2-hydroxy-3-(4-(1-(4-isopropy...)
Affinity DataKi:  34nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247972((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-(4-methylfuran-...)
Affinity DataKi:  35nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248589(2-hydroxy-N,N-dimethyl-3-(4-(2,2,2-trifluoro-1-phe...)
Affinity DataKi:  36nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248112((R)-3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  38nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248546((S)-3-(4-(3,3-dimethylbutan-2-ylamino)-1,2,5-thiad...)
Affinity DataKi:  43nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248592((R)-3-(4-(1-(2,3-dihydro-1H-inden-5-yl)-2,2-dimeth...)
Affinity DataKi:  44nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248115((R)-N-(2-cyanoethyl)-3-(4-(1-(furan-2-yl)-2,2-dime...)
Affinity DataKi:  44nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247947((R)-3-(4-(1-(benzo[d][1,3]dioxol-5-yl)-2,2-dimethy...)
Affinity DataKi:  52nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248036((S)-2-hydroxy-N,N-dimethyl-3-(4-(2,2,2-trifluoro-1...)
Affinity DataKi:  53nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248081((R)-3-(4-(1-(benzofuran-2-yl)-2,2-dimethylpropylam...)
Affinity DataKi:  76nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247949((R)-3-(4-(1-(3-fluorophenyl)-2,2-dimethylpropylami...)
Affinity DataKi:  78nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248114((R)-N-(2-cyanoethyl)-2-hydroxy-3-(4-(1-(4-isopropy...)
Affinity DataKi:  79nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248038((R)-3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  91nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248113((R)-N-(2-cyanoethyl)-3-(4-(2,2-dimethyl-1-(5-methy...)
Affinity DataKi:  114nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247948((R)-3-(4-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-...)
Affinity DataKi:  126nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248112((R)-3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  168nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247947((R)-3-(4-(1-(benzo[d][1,3]dioxol-5-yl)-2,2-dimethy...)
Affinity DataKi:  330nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248039((R)-3-(4-(1-(furan-2-yl)-2,2-dimethylpropylamino)-...)
Affinity DataKi:  381nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248084((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-(5-methylfuran-...)
Affinity DataKi:  749nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248083((R)-(3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)prop...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248082((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247949((R)-3-(4-(1-(3-fluorophenyl)-2,2-dimethylpropylami...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248591((R)-3-(4-(cyclopropyl(phenyl)methylamino)-1,2,5-th...)
Affinity DataKi:  2.03E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247972((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-(4-methylfuran-...)
Affinity DataKi:  2.28E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248081((R)-3-(4-(1-(benzofuran-2-yl)-2,2-dimethylpropylam...)
Affinity DataKi:  2.36E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247950((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-(5-methylfuran-...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248590((R)-3-(4-(1-(3,5-difluorophenyl)propylamino)-1,2,5...)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248589(2-hydroxy-N,N-dimethyl-3-(4-(2,2,2-trifluoro-1-phe...)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248547((R)-2-hydroxy-N,N-dimethyl-3-(4-(1-phenylpropylami...)
Affinity DataKi:  5.11E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248036((S)-2-hydroxy-N,N-dimethyl-3-(4-(2,2,2-trifluoro-1...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50247948((R)-3-(4-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248592((R)-3-(4-(1-(2,3-dihydro-1H-inden-5-yl)-2,2-dimeth...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248546((S)-3-(4-(3,3-dimethylbutan-2-ylamino)-1,2,5-thiad...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248038((R)-3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50:  21nMAssay Description:Displacement of [125I]CXCL1 from CXCR2 receptor in human PMN assessed as myeloperoxidase releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataIC50:  36nMAssay Description:Displacement of [125I]CXCL1 from CXCR2 receptor in human PMN assessed as myeloperoxidase releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248038((R)-3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50:  143nMAssay Description:Displacement of [125I]CXCL8 from CXCR1 receptor in human PMN assessed as myeloperoxidase releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataIC50:  3.91E+3nMAssay Description:Displacement of [125I]CXCL8 from CXCR1 receptor in human PMN assessed as myeloperoxidase releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed