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Found 19 Enz. Inhib. hit(s) with all data for entry = 50028537
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50091801(6-Isobutyl-4-methyl-pyridin-2-ylamine | 6-isobutyl...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267278(6-(3-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50:  57.6nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50091801(6-Isobutyl-4-methyl-pyridin-2-ylamine | 6-isobutyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50091801(6-Isobutyl-4-methyl-pyridin-2-ylamine | 6-isobutyl...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human eNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267355(6-(4-Fluorobutyl)-4-methylpyridin-2-amine | CHEMBL...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50091801(6-Isobutyl-4-methyl-pyridin-2-ylamine | 6-isobutyl...)
Affinity DataIC50:  193nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267272(6-(2-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267274((E)-4-Methyl-6-(prop-1-enyl)pyridin-2-amine | CHEM...)
Affinity DataIC50:  282nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267272(6-(2-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50:  490nMAssay Description:Inhibition of human recombinant nNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267278(6-(3-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50:  514nMAssay Description:Inhibition of human recombinant nNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267273(4-Methyl-6-(2-methylprop-1-enyl)pyridin-2-amine | ...)
Affinity DataIC50:  685nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267408(6-(4-Fluoro-2-methylbutyl)-4-methylpyridin-2-amine...)
Affinity DataIC50:  731nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267278(6-(3-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of human recombinant eNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267272(6-(2-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant eNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267275(1-(6-Amino-4-methylpyridin-2-yl)propan-2-ol | CHEM...)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267276(6-(2-Methoxypropyl)-4-methylpyridin-2-amine | CHEM...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267409(6-(4-Methoxy-2-methylbutyl)-4-methylpyridin-2-amin...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267410(4-Methyl-6-(2-methyl-4-(methylthio)butyl)pyridin-2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50267277(6-(2-(2-Fluoroethoxy)propyl)-4-methylpyridin-2-ami...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed