Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50028719
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258551((S)-N-hydroxy-7-(2-(5-methoxy-2-methyl-1H-indol-3-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258625((S)-7-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)-7-(2-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258582((S)-7-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)-7-(th...)
Affinity DataIC50:  23nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50:  27nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258549((S)-2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-(1-(5-(...)
Affinity DataIC50:  27nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258550((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  28nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  30nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258552((S)-N-methoxy-7-(2-(5-methoxy-2-methyl-1H-indol-3-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258624((S)-7-(1-methylpiperidine-4-carboxamido)-7-(5-(nap...)
Affinity DataIC50:  35nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258584((S)-7-((S)-1-methylpyrrolidine-3-carboxamido)-7-(5...)
Affinity DataIC50:  40nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  43nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50:  44nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258553((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  47nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  57nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258627((S)-N-ethyl-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50:  66nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258583((S)-7-((R)-1-methylpyrrolidine-3-carboxamido)-7-(5...)
Affinity DataIC50:  73nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  82nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258554((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  94nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258633((S)-N-(2-aminophenyl)-7-(2-(5-methoxy-2-methyl-1H-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258555((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  120nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  120nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  160nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258631((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  170nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258630((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  200nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258585((S)-7-(N,N-dimethylsulfamoylamino)-7-(5-(naphthale...)
Affinity DataIC50:  220nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  250nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258632((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50:  350nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258628((S)-N-isopropyl-7-(2-(5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  480nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258629((S)-N-benzyl-7-(2-(5-methoxy-2-methyl-1H-indol-3-y...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of His-tagged HDAC8 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of His-tagged HDAC8 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed