Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50031455
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50234162((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313630((6R,7S,7aS)-2-((1H-pyrazol-5-yl)methylamino)-6-((R...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313629((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313629((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313620((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313622((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313620((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313624((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313621((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313632((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313632((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313628((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313624((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313624((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313628((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313623((6R,7S,7aR)-1-((1H-pyrazol-5-yl)methylamino)-6-((R...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313631((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313626((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313626((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313627((6R,7S,7aS)-2-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313627((6R,7S,7aS)-2-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313625(1-((2R,3S,4R)-4-((R)-1-(3,5-bis(trifluoromethyl)ph...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313621((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.420nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313624((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313624((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313624((6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313622((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.830nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313630((6R,7S,7aS)-2-((1H-pyrazol-5-yl)methylamino)-6-((R...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313620((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313620((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313631((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313629((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313623((6R,7S,7aR)-1-((1H-pyrazol-5-yl)methylamino)-6-((R...)
Affinity DataIC50:  1.83nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313629((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313627((6R,7S,7aS)-2-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313627((6R,7S,7aS)-2-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313632((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313632((6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50234162((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313628((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313628((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313626((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313626((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313625(1-((2R,3S,4R)-4-((R)-1-(3,5-bis(trifluoromethyl)ph...)
Affinity DataIC50:  43.1nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in the presence of 50 percent human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed