Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50031517
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314628((E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)pyrr...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314630((E)-N-Hydroxy-3-(4-{1-[2-(2-methyl-1H-indol-3-yl)e...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314637((E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314627((E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)pipe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314642((E)-3-{4-[(R)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314642((E)-3-{4-[(R)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  9nMAssay Description:Inhibition of FLAG-tagged HDAC3 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  9nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314640((E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314636((E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)pipe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314635((E)-N-Hydroxy-3-{4-[3-(1H-indol-3-yl)piperidin-1-y...)
Affinity DataIC50:  11nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314633(CHEMBL1093362 | N-hydroxy-3-(2-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  13nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314643((E)-3-{4-[(S)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  15nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314639((E)-3-{3-Fluoro-4-[3-(2-phenyl-1H-indol-3-yl)piper...)
Affinity DataIC50:  16nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314641((E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314643((E)-3-{4-[(S)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  21nMAssay Description:Inhibition of FLAG-tagged HDAC3 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314629((E)-N-Hydroxy-3-{4-[2-(2-methyl-1H-indol-3-ylmethy...)
Affinity DataIC50:  24nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314631(CHEMBL1088949 | N-hydroxy-3-(2-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  27nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314642((E)-3-{4-[(R)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  28nMAssay Description:Inhibition of HDAC4 expressed in baculovirus system by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314642((E)-3-{4-[(R)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  31nMAssay Description:Inhibition of HDAC2 expressed in baculovirus system by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314643((E)-3-{4-[(S)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HDAC4 expressed in baculovirus system by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314632(CHEMBL1089701 | N-hydroxy-3-(2-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  41nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314643((E)-3-{4-[(S)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  48nMAssay Description:Inhibition of HDAC2 expressed in baculovirus system by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314634(CHEMBL1089301 | N-hydroxy-3-(3-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  76nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314643((E)-3-{4-[(S)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of FLAG-tagged HDAC6 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314642((E)-3-{4-[(R)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  118nMAssay Description:Inhibition of FLAG-tagged HDAC6 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314638((E)-3-{3-Fluoro-4-[3-(1H-indol-3-yl)piperidin-1-yl...)
Affinity DataIC50:  136nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314642((E)-3-{4-[(R)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  217nMAssay Description:Inhibition of HDAC8 expressed in baculovirus system by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314643((E)-3-{4-[(S)-3-(2-tert-Butyl-1H-indol-3-yl)piperi...)
Affinity DataIC50:  364nMAssay Description:Inhibition of HDAC8 expressed in baculovirus system by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314633(CHEMBL1093362 | N-hydroxy-3-(2-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314634(CHEMBL1089301 | N-hydroxy-3-(3-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314631(CHEMBL1088949 | N-hydroxy-3-(2-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314629((E)-N-Hydroxy-3-{4-[2-(2-methyl-1H-indol-3-ylmethy...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314641((E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314628((E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)pyrr...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314637((E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314632(CHEMBL1089701 | N-hydroxy-3-(2-(2-(2-methyl-1H-ind...)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314638((E)-3-{3-Fluoro-4-[3-(1H-indol-3-yl)piperidin-1-yl...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314639((E)-3-{3-Fluoro-4-[3-(2-phenyl-1H-indol-3-yl)piper...)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314630((E)-N-Hydroxy-3-(4-{1-[2-(2-methyl-1H-indol-3-yl)e...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314627((E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)pipe...)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314636((E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)pipe...)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314635((E)-N-Hydroxy-3-{4-[3-(1H-indol-3-yl)piperidin-1-y...)
Affinity DataIC50:  2.93E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314640((E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed