Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50032011
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50:  10nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50:  20nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323223((2S,3S)-N-(4-(5-(2-cyclohexylethyl)-1,2,4-oxadiazo...)
Affinity DataIC50:  25nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323219((2S,3S)-N-((S)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323220((2S,3S)-N-((S)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  48nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323231((2S,3S)-N-(4-(5-hexyl-1,2,4-oxadiazol-3-yl)benzyl)...)
Affinity DataIC50:  49nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323242((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50:  56nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323234((2S,3S)-N-(4-(3-heptyl-1,2,4-oxadiazol-5-yl)benzyl...)
Affinity DataIC50:  61nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50299328((2S,3S)-3-hydroxy-N-(4-octylphenyl)pyrrolidine-2-c...)
Affinity DataIC50:  62nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323225((2S,3S)-N-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiaz...)
Affinity DataIC50:  68nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50:  68nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323233((2S,3S)-N-(4-(5-heptylthiazol-2-yl)benzyl)-3-hydro...)
Affinity DataIC50:  70nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323238((2S,3S)-3-hydroxy-N-(4-(5-octyl-1,2,4-oxadiazol-3-...)
Affinity DataIC50:  86nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323218((2S,3S)-N-((S)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  110nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323228((2S,3S)-3-hydroxy-N-(4-(5-(1-methylcyclohexyl)-1,2...)
Affinity DataIC50:  210nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323229((2S,3S)-N-(4-(5-cyclohexyl-1,2,4-oxadiazol-3-yl)be...)
Affinity DataIC50:  380nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323230((2S,3S)-3-hydroxy-N-(4-(5-pentyl-1,2,4-oxadiazol-3...)
Affinity DataIC50:  430nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323237((2S,3S)-N-(4-(5-heptyl-1-methyl-1H-1,2,4-triazol-3...)
Affinity DataIC50:  610nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323226((2S,3S)-N-(4-(5-cycloheptyl-1,2,4-oxadiazol-3-yl)b...)
Affinity DataIC50:  620nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323222((2S,3S)-3-hydroxy-N-(4-(5-phenethyl-1,2,4-oxadiazo...)
Affinity DataIC50:  720nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323232((2S,3S)-N-(4-(5-heptyl-1H-pyrazol-3-yl)benzyl)-3-h...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323235((2S,3S)-N-(4-(4-heptyl-1H-1,2,3-triazol-1-yl)benzy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323236((2S,3S)-N-(4-(5-heptyl-1,3,4-oxadiazol-2-yl)benzyl...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323227((2S,3S)-N-(4-(5-cyclopentyl-1,2,4-oxadiazol-3-yl)b...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323221((2S,3S)-N-((R)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323224((2S,3S)-N-(4-(5-(2-cyclopropylethyl)-1,2,4-oxadiaz...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323239((2S,3S)-3-hydroxy-N-(4-(5-octyl-1,2,4-oxadiazol-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50323241((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed