Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50033485
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346239((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346240((7-ethoxybenzofuran-2-yl)(5-(2-hydroxyphenyl)-3-(p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346241((5-bromofuran-2-yl)(5-(2-hydroxyphenyl)-3-(pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346239((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346240((7-ethoxybenzofuran-2-yl)(5-(2-hydroxyphenyl)-3-(p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346241((5-bromofuran-2-yl)(5-(2-hydroxyphenyl)-3-(pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346239((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346240((7-ethoxybenzofuran-2-yl)(5-(2-hydroxyphenyl)-3-(p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346241((5-bromofuran-2-yl)(5-(2-hydroxyphenyl)-3-(pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346239((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346240((7-ethoxybenzofuran-2-yl)(5-(2-hydroxyphenyl)-3-(p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346241((5-bromofuran-2-yl)(5-(2-hydroxyphenyl)-3-(pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346239((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346240((7-ethoxybenzofuran-2-yl)(5-(2-hydroxyphenyl)-3-(p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346241((5-bromofuran-2-yl)(5-(2-hydroxyphenyl)-3-(pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase ICK(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346239((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346240((7-ethoxybenzofuran-2-yl)(5-(2-hydroxyphenyl)-3-(p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346241((5-bromofuran-2-yl)(5-(2-hydroxyphenyl)-3-(pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed