Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50032431
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329111(2-(6-(4,6-di(pyrrolidin-1-yl)-1,3,5-triazin-2-ylam...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329112(2-(6-(4,6-di(pyrrolidin-1-yl)-1,3,5-triazin-2-ylam...)
Affinity DataIC50:  690nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329113(CHEMBL1270780 | N-benzyl-2-(6-(4,6-di(pyrrolidin-1...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329114(CHEMBL1270883 | ethyl 2-(6-(4,6-di(pyrrolidin-1-yl...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329115(2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylami...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329116(2-(6-(4,6-di(pyrrolidin-1-yl)-1,3,5-triazin-2-ylam...)
Affinity DataIC50:  2.83E+3nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329117(2-(6-(4,6-di(pyrrolidin-1-yl)-1,3,5-triazin-2-ylam...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329118(1-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-2-(6-...)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329119(2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylami...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329120(2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylami...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329121(2-(6-(4,6-di(pyrrolidin-1-yl)-1,3,5-triazin-2-ylam...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329122(2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylami...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329110(2-(6-(4,6-dimorpholino-1,3,5-triazin-2-ylamino)ben...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329126(2-(6-(4,6-dimorpholino-1,3,5-triazin-2-ylamino)ben...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329123(2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylami...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329125(CHEMBL1270082 | N-(2-chlorophenyl)-2-(6-(4,6-dimor...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329124(CHEMBL1269866 | N-benzyl-2-(6-(4,6-dimorpholino-1,...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed