Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50032446
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329390(4'-(5-(1-(4-tert-butylphenyl)-1-hydroxy-3-(pyrroli...)
Affinity DataKi:  40nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329389(4'-(5-(1-(4-tert-butylphenyl)-1-hydroxy-3-morpholi...)
Affinity DataKi:  110nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329388(4'-(5-(1-(4-bromophenyl)-1-hydroxy-3-morpholinopro...)
Affinity DataKi:  200nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329386(4'-(2-chloro-5-(1-(4-chlorophenyl)-1-hydroxy-3-mor...)
Affinity DataKi:  220nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329387(4'-(2-chloro-5-(1-(4-chlorophenyl)-1-hydroxyethyl)...)
Affinity DataKi:  460nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329380(4'-(2-(3-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329385(4'-(2-(4-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329379(4'-(3-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)p...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329378(4'-(2-(3-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329375(3'-(2-(3-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329377(4'-((3-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)...)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329381(3'-((4-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329382(3'-(2-(4-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329384(4'-(2-(4-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329376(3'-((3-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329383(4'-((4-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)...)
Affinity DataKi:  8.30E+4nMAssay Description:Inhibition of Bcl-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329370(4-(dimethylamino)-1,1-diphenylbutan-1-ol | CHEMBL1...)
Affinity DataKd:  5.00E+6nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329371(1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperaz...)
Affinity DataKd:  7.00E+5nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329374(4'-ethyl-biphenyl-4-carboxylic acid | 4'-ethylbiph...)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to Bcl-2 by NMR titration assay in presence of 500 uM 1,1-bis(4-chlorophenyl)-3-(dimethylamino)propan-1-olMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329374(4'-ethyl-biphenyl-4-carboxylic acid | 4'-ethylbiph...)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329373(3'-ethylbiphenyl-4-carboxylic acid | CHEMBL1269503)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to Bcl-2 by NMR titration assay in presence of 500 uM 1,1-bis(4-chlorophenyl)-3-(dimethylamino)propan-1-olMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329373(3'-ethylbiphenyl-4-carboxylic acid | CHEMBL1269503)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060993(4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID | 4'-Flu...)
Affinity DataKd:  4.30E+5nMAssay Description:Binding affinity to Bcl-2 by NMR titration assay in presence of 500 uM 1,1-bis(4-chlorophenyl)-3-(dimethylamino)propan-1-olMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060993(4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID | 4'-Flu...)
Affinity DataKd:  4.00E+5nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329372((S)-2-amino-1-(2-chloro-4-fluorophenyl)-1-phenylet...)
Affinity DataKd:  2.50E+5nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329371(1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperaz...)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329370(4-(dimethylamino)-1,1-diphenylbutan-1-ol | CHEMBL1...)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329369((R)-1-(4-chlorophenyl)-4-(dimethylamino)-1-phenylb...)
Affinity DataKd:  8.00E+4nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329369((R)-1-(4-chlorophenyl)-4-(dimethylamino)-1-phenylb...)
Affinity DataKd:  5.00E+5nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329368(1,1-bis(4-chlorophenyl)-4-(dimethylamino)butan-1-o...)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to Bcl-2 by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329368(1,1-bis(4-chlorophenyl)-4-(dimethylamino)butan-1-o...)
Affinity DataKd:  4.50E+5nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed