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Found 10 Enz. Inhib. hit(s) with all data for entry = 50034633
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50365396(CHEMBL1956397)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50365396(CHEMBL1956397)
Affinity DataIC50:  830nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50365396(CHEMBL1956397)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50365396(CHEMBL1956397)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  6.39E+4nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50365396(CHEMBL1956397)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed