Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50034651
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant PI3Kdelta HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant PI3Kbeta HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant PI3Kgamma HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50365736(CHEMBL1956189)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50365735(CHEMBL33859 | MKT-077 | US20230414581, Compound 39)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed