Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50040677
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26626((5Z)-5-{[3-(trifluoromethyl)phenyl]methylidene}-1,...)
Affinity DataKi:  24nMAssay Description:Competitive inhibition of PIM1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26626((5Z)-5-{[3-(trifluoromethyl)phenyl]methylidene}-1,...)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of PIM2 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364776(CHEMBL1952141 | CHEMBL1952329)
Affinity DataIC50:  7nMAssay Description:Competitive inhibition of PIM1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50398243(CHEMBL2177299)
Affinity DataIC50:  20nMAssay Description:Competitive inhibition of PIM1 using KKRNRTLTV as substrate after 5 mins by scintillation counter in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364776(CHEMBL1952141 | CHEMBL1952329)
Affinity DataIC50:  34nMAssay Description:Inhibition of haspinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM28394((2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2...)
Affinity DataIC50:  40nMAssay Description:Competitive inhibition of PIM2 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364776(CHEMBL1952141 | CHEMBL1952329)
Affinity DataIC50:  44nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26673(6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dih...)
Affinity DataIC50:  50nMAssay Description:Competitive inhibition of PIM1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM28394((2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2...)
Affinity DataIC50:  57nMAssay Description:Competitive inhibition of PIM1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50398243(CHEMBL2177299)
Affinity DataIC50:  63nMAssay Description:Competitive inhibition of CK2alpha using RRREDEESDDEE as substrate after 5 mins by scintillation counter in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364776(CHEMBL1952141 | CHEMBL1952329)
Affinity DataIC50:  69nMAssay Description:Competitive inhibition of PIM3 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364776(CHEMBL1952141 | CHEMBL1952329)
Affinity DataIC50:  363nMAssay Description:Competitive inhibition of PIM2 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  1.10E+3nMAssay Description:Competitive inhibition of PIM1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17055((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...)
Affinity DataKd:  130nMAssay Description:Competitive binding affinity to PIM2 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17055((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...)
Affinity DataKd:  50nMAssay Description:Competitive binding affinity to PIM1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed