Compile Data Set for Download or QSAR
maximum 50k data
Found 68 Enz. Inhib. hit(s) with all data for entry = 50042693
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50:  3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429516(CHEMBL2333334)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097370(1-((1H-imidazol-1-yl)methyl)-4-bromo-9H-xanthen-9-...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097370(1-((1H-imidazol-1-yl)methyl)-4-bromo-9H-xanthen-9-...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097365(1-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-4-c...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429517(CHEMBL2333333)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429520(CHEMBL2333330)
Affinity DataIC50:  15nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429517(CHEMBL2333333)
Affinity DataIC50:  15nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429523(CHEMBL2333327)
Affinity DataIC50:  19nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429519(CHEMBL2333331)
Affinity DataIC50:  19nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097365(1-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-4-c...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097363(1-((1H-imidazol-1-yl)methyl)-4-nitro-9H-xanthen-9-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429516(CHEMBL2333334)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429518(CHEMBL2333332)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429523(CHEMBL2333327)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429518(CHEMBL2333332)
Affinity DataIC50:  25nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429520(CHEMBL2333330)
Affinity DataIC50:  25nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097363(1-((1H-imidazol-1-yl)methyl)-4-nitro-9H-xanthen-9-...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429521(CHEMBL2333329)
Affinity DataIC50:  41nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097370(1-((1H-imidazol-1-yl)methyl)-4-bromo-9H-xanthen-9-...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429521(CHEMBL2333329)
Affinity DataIC50:  80nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429519(CHEMBL2333331)
Affinity DataIC50:  93nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50318619(1-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083652)
Affinity DataIC50:  99nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429515(CHEMBL2333335)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429522(CHEMBL2333328)
Affinity DataIC50:  104nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50318619(1-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083652)
Affinity DataIC50:  114nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097363(1-((1H-imidazol-1-yl)methyl)-4-nitro-9H-xanthen-9-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429522(CHEMBL2333328)
Affinity DataIC50:  156nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429514(CHEMBL2333336)
Affinity DataIC50:  170nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097365(1-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-4-c...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429514(CHEMBL2333336)
Affinity DataIC50:  235nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429515(CHEMBL2333335)
Affinity DataIC50:  260nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50:  260nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429515(CHEMBL2333335)
Affinity DataIC50:  268nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429522(CHEMBL2333328)
Affinity DataIC50:  300nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429519(CHEMBL2333331)
Affinity DataIC50:  400nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429514(CHEMBL2333336)
Affinity DataIC50:  416nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429523(CHEMBL2333327)
Affinity DataIC50:  460nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50:  480nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429514(CHEMBL2333336)
Affinity DataIC50:  493nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429516(CHEMBL2333334)
Affinity DataIC50:  565nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429517(CHEMBL2333333)
Affinity DataIC50:  575nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429521(CHEMBL2333329)
Affinity DataIC50:  610nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429513(CHEMBL2333337)
Affinity DataIC50:  677nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50429513(CHEMBL2333337)
Affinity DataIC50:  785nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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