Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 6806
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Peking University

LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  5.30E+3nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Peking University

LigandPNGBDBM152734(11-bromo-5-[4-(2-fluorophenyl)piperazine-1- carbon...)
Affinity DataIC50:  5.70E+3nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Peking University

LigandPNGBDBM152736(5-(4-benzylpiperazine-1-carbonyl)-11-bromo-8,10-di...)
Affinity DataIC50:  2.10E+4nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Peking University

LigandPNGBDBM152735(11-bromo-5-{4-[4-(trifluoromethoxy)phenyl]piperazi...)
Affinity DataIC50:  8.60E+4nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed