Found 19 Enz. Inhib. hit(s) with all data for entry = 50045097 Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataKi: 7.70E+3nMAssay Description:Uncompetitive inhibition of His-tagged Escherichia coli DXR at 1 to 8 uM pre-incubated for 2 mins before reaction initiation in presence of 160 uM NA...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 400nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in presence of 0.01% Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in presence of 0.01% Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in presence of 0.01% Triton X100 by ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
