Found 35 Enz. Inhib. hit(s) with all data for entry = 50006160 
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >100nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 152nMAssay Description:Binding affinity to serotonin 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to muscarinic M5 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to serotonin 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to alpha1-adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA systemMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA systemMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as [3H]PI metabolismMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA systemMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as [3H]PI metabolismMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Antagonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as [3H]PI metabolismMore data for this Ligand-Target Pair
