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Found 14 Enz. Inhib. hit(s) with all data for entry = 50046017
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as whole cell current by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50:  932nMAssay Description:Inhibition of human recombinant CYP3A4 using midazolam as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using testosterone as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using testosterone as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50:  4.78E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using midazolam as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50:  8.11E+3nMAssay Description:Inhibition of human recombinant CYP2C19 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50:  8.54E+3nMAssay Description:Inhibition of human recombinant CYP2C9 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of human recombinant CYP2C19 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as whole cell current by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP1A2 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP2C9 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP2D6 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP2D6 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP1A2 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed