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Found 9 Enz. Inhib. hit(s) with all data for entry = 50046887
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataIC50:  40nMAssay Description:Inhibition of wild-type FLT3 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataIC50:  421nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataIC50:  559nMAssay Description:Inhibition of c-KIT (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 mediated Stat5 phosphorylation in human MOLM14 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MV4-11 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 mediated Stat5 phosphorylation in human MV4-11 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50:  100nMAssay Description:Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MOLM13 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MOLM14 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 mediated Stat5 phosphorylation in human MOLM13 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed