Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50006592
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  120nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 40) production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  130nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 42) production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50500995(CHEMBL3799376)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50500994(CHEMBL3798465)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed