Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50047189
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataKi:  1.10nMAssay Description:Competitive inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-alpha-methylglucoside uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50152828(Apatinib | YN-968D1)
Affinity DataIC50:  1nMAssay Description:Inhibition of VEGF2 receptor (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50152829(CHEMBL3780740)
Affinity DataIC50:  18nMAssay Description:Agonist activity at PPAR-gamma receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50152829(CHEMBL3780740)
Affinity DataIC50:  20nMAssay Description:Agonist activity at PPAR-alpha receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed