Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50047504
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172062(CHEMBL3806108)
Affinity DataIC50:  870nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172059(CHEMBL3805508)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172060(CHEMBL3805409)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172061(CHEMBL3805893)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172058(CHEMBL3805675)
Affinity DataIC50:  2.62E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172063(CHEMBL3805849)
Affinity DataIC50:  3.37E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172061(CHEMBL3805893)
Affinity DataIC50:  5.17E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172062(CHEMBL3806108)
Affinity DataIC50:  5.48E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172059(CHEMBL3805508)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172059(CHEMBL3805508)
Affinity DataIC50:  7.92E+3nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172063(CHEMBL3805849)
Affinity DataIC50:  8.35E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172061(CHEMBL3805893)
Affinity DataIC50:  9.04E+3nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172060(CHEMBL3805409)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172058(CHEMBL3805675)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172060(CHEMBL3805409)
Affinity DataIC50:  8.12E+4nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172063(CHEMBL3805849)
Affinity DataIC50:  1.92E+5nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172058(CHEMBL3805675)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50172062(CHEMBL3806108)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed