Affinity DataIC50: 870nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
Affinity DataIC50: 7.92E+3nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
Affinity DataIC50: 9.04E+3nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair
Affinity DataIC50: 8.12E+4nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+5nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair