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Found 14 Enz. Inhib. hit(s) with all data for entry = 50010017
TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  14nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  96nMAssay Description:Inhibition of electric eel AChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  107nMAssay Description:Inhibition of electric eel AChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50534411(CHEMBL4578033)
Affinity DataIC50:  443nMAssay Description:Inhibition of human BuChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assayMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  495nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50534411(CHEMBL4578033)
Affinity DataIC50:  763nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  803nMAssay Description:Inhibition of human BuChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  5.91E+3nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  6.33E+3nMAssay Description:Inhibition of human AChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50534413(CHEMBL4451368)
Affinity DataIC50:  9.72E+3nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50534412(CHEMBL4545740)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50534410(CHEMBL4520824)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50534414(CHEMBL4452331)
Affinity DataIC50:  4.89E+4nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  7.42E+4nMAssay Description:Inhibition of electric eel AChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed