Found 12 Enz. Inhib. hit(s) with all data for entry = 50010244 
Affinity DataKi: 25nMAssay Description:Displacement of europium-labeled SRC1 peptide from full length human recombinant ERalpha expressed in baculovirus expression system after 1.5 hrs in ...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of AR transcriptional activity in human ARR2PB-eGFP expressing LNCaP cells after 3 days by fluorescence assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 566nMAssay Description:Binding affinity to human 6xHis-tagged PPARgamma ligand binding domain (206 to 477 residues) by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of full length human ERalpha expressed in human HEC1 cells in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+3nMAssay Description:Displacement of fluorescein-labeled PGC1alpha peptide from human GST-tagged ERalpha LBD after 2 hrs in presence of estradiol-beta by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.98E+3nMAssay Description:Displacement of fluorescein-labeled PGC1alpha peptide from human GST-tagged ERalpha LBD after 2 hrs in presence of estradiol-beta by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of full length human ERalpha expressed in human HEC1 cells in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human GST-tagged RXRalpha ligand binding domain (223 to 462 residues) expressed in Escherichia coli BL21 assessed as inhibition o...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human GST-tagged RXRalpha ligand binding domain (223 to 462 residues) expressed in Escherichia coli BL21 assessed as inhibition o...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 80nMAssay Description:Displacement of 5-FAM-labeled NBM131 from human PPARalpha ligand binding domain expressed in human HepG2 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 513nMAssay Description:Binding affinity to N-terminal His6-tagged human PPARgamma (205 to 477 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 80nMAssay Description:Displacement of 5-FAM-labeled NBM131 from human PPARgamma ligand binding domain expressed in human HepG2 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
